kenmochi laboratory


Patil, P., Kibiryeva, N., Uechi, T., Marshall, J., Artman, M., O'Brien, J.E., Kenmochi, N. and Bittel, D.C.

scaRNAs regulate splicing and vertebrate heart development.

Biochem. Biophys. Acta (in press)

Patil P, Uechi T, Kenmochi N

Incomplete splicing of neutrophil-specific genes affects neutrophil development in a zebrafish model of poikiloderma with neutropenia

RNA Biology, 12(4):426-434. 2015

Wang R, Yoshida K, Toki T, Sawada T, Uechi T, Okuno Y, Sato-Otsubo A, Kudo K, Kamimaki I, Kanezaki R, Shiraishi Y, Chiba K, Tanaka H, Terui K, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Hara J, Goi K, Matsubara K, Koike K, Ishiguro A, Okamoto Y, Watanabe K, Kanno H, Kojima S, Miyano S, Kenmochi N, Ogawa S, Ito E.

Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.

Br J Haematol, 168(6):854-864. 2015

Yamamoto T, Yamamori K, Kenmochi N, Aikawa M

A detection method for snoRNA modification domain by fully indexable dictionary retrieving

Artif Life Robotics, 19:209-214. 2014

Yadav VG, Chakraborty A, Uechi T, Kenmochi N

Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish

Int J Biochem Cell Biol, 49: 1-7. 2014

Yoshihama M, Nakao A, Kenmochi N

snOPY: a small nucleolar RNA orthological gene database

BMC Research Notes, 6: 426. 2013

Yamamori K, Matsuo T, Iwakiri J, Kenmochi N, Yoshihara I

A detection method for intronic snoRNA genes using extended- weight-updating SOM with appearance probability of bases

Artificial Life and Robotics, 17(3-4): 405-411. 2013

Chakraborty A, Kenmochi N

Ribosomes and Ribosomal Proteins: More Than Just ‘Housekeeping’

In: eLS 2012, John Wiley & Sons Ltd: Chichester [DOI:10.1002/9780470015902.a0005055.pub2]

Iwakiri J, Tateishi H, Chakraborty A, Patil P, Kenmochi N

Dissecting the protein-RNA interface: the role of protein surface shapes and RNA secondary structures in protein-RNA recognition

Nucleic Acids Res, 40(8): 3299-3306. 2012

Higa-Nakamine S, Suzuki T, Uechi T, Chakraborty A, Nakajima Y, Nakamura M, Hirano N, Suzuki T, Kenmochi N

Loss of ribosomal RNA modification causes developmental defects in zebrafish

Nucleic Acids Res, 40(1): 391-398. 2012

Chakraborty A, Uechi T, Kenmochi N

Guarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathway

WIREs RNA, 2(4): 507-522. 2011

Kenmochi N

Eukaryotic small RNAs

The molecular biology of non-coding RNA. KUBAPURO 2010 (In Japanese)

Ikeda M, Andoo A, Shimono M, Takamatsu N, Taki A, Muta K, Matsushita W, Uechi T, Matsuzaki T, Kenmochi N, Takata K, Sasaki S, Ito K, Ishibashi K

The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function

J. Biol. Chem, 286(5): 3342-3350. 2011

Torihara H, Uechi T, Chakraborty A, Shinya M, Sakai N, Kenmochi N

Erythropoiesis failure due to RPS19 deficiency is independent of an activated p53 response in a zebrafish model of Diamond-Blackfan anaemia

British Journal of Haematology, 1365-2141. 2010

Higa S, Kenmochi N

Functional analysis of RNA modification in zebrafish

Protein,Nucleic Acid and Enzyme:mRNA program. 2092-2097. 2009 (In Japanese)

Uechi T, Kenmochi N

Ribosome Disease: Translation Apparatus System Failure

Gene and Medicine MOOK: New RNA and Disease Research. 79-84. 2009 (In Japanese)

Chakraborty A, Uechi T, Higa S, Torihara H, Kenmochi N

Loss of Ribosomal Protein L11 Affects Zebrafish Embryonic Development through a p53-Dependent Apoptotic Response

PLoS ONE 4(1): e4152. 2009

Uechi T, Nakajima Y, Chakraborty A, Torihara H, Higa S, Kenmochi N

Deficiency of ribosomal protein S19 during early embryogenesis leads to reduction of erythrocytes in a zebrafish model of Diamond-Blackfan anemia.

Hum Mol Genet. 17(20): 3204-3211. 2008

Kenmochi N

Evolution of intron encoded functional RNA

Biological Science: Theory and features of modern Medicine and Biological Hypothesis: 59(5): 386-387. 2008 (In Japanese)

Marygold S, Roote J, Reuter G, Lambertsson A, Ashburner M, Millburn M, Harrison P, Yu Z, Kenmochi N, Kaufman TC, Leevers SJ, Cook KR.

The ribosomal protein genes and Minute loci of Drosophila melanogaster.

Genome Biol. 8:R216. 2007

Nguyen HD, Yoshihama M, Kenmochi N.

The evolution of spliceosomal introns in alveolates.

Mol Biol Evol. 24(5): 1093-1096. 2007

Nguyen HD, Yoshihara I, Yamamori K, Yasunaga M.

Implementation of an effective hybrid GA for large-scale traveling salesman problems.

IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics 37(1): 92-99. 2007

Yoshihama M, Nguyen HD, Kenmochi N.

Intron dynamics in ribosomal protein genes.

PLoS ONE 2(1): e141. 2007

Uechi T, Nakajima Y, Nakao A, Torihara H, Chakraborty A, Inoue K, Kenmochi N.

Ribosomal protein gene knockdown causes developmental defects in zebrafish.

PLoS ONE 1(1): e37. 2006

Kenmochi N

Intron evolution

Biological science: molecular map of biological evolution, 57: 347-349. 2006 (In Japanese)

Nguyen HD, Yoshihama M, Kenmochi N.

Phase distribution of spliceosomal introns: implications for intron origin.

BMC Evol. Biol. 6:69. 2006  

Kenmochi N

Genetic Analysis of snoRNA:An approach using zebrafish

Functional Non-coding RNA. 83-98. 2006 (In Japanese)

Yoshihama M, Nakao A, Nguyen HD, Kenmochi N.

Analysis of ribosomal protein gene structures: implications for intron evolution.

PLoS Genet. 2(3): e25. 2006

Ishii K, Washio T, Uechi T, Yoshihama M, Kenmochi N, Tomita M.

Characteristics and clustering of human ribosomal protein genes.

BMC Genomics. 7(1): 37. 2006

Maeda N, Toku S, Kenmochi N, Tanaka T.

A novel nucleolar protein interacts with ribosomal protein S19.

Biochem Biophys Res Commun. 339(1): 41-46. 2006

Nguyen HD, Yoshihama M, Kenmochi N.

New maximum likelihood estimators for eukaryotic intron evolution.

PLoS Comput Biol. 1(7):e79. 2005

Nakao A, Yoshihama M, Kenmochi N.

RPG: the Ribosomal Protein Gene database.

Nucleic Acids Res. 32(Database issue):D168-170. 2004

Kenmochi N

Ribosome and disease

Experimental Medicine(supplement)22: 200-205. 2004 (In Japanese)

Kenmochi N.

Ribosomes and Ribosomal Proteins.

In:Cooper DN (ed.) Nature Encyclopedia of the Human Genome.

Nature Publishing Group, London, 5: 77-82. 2003

Kenmochi N

Ribosome Disease: Exploring the possibility of a new disease

Protein, Nucleic Acid and Enzyme (supplement)48: 508-516. 2003 (In Japanese)

Uechi T, Maeda N, Tanaka T, Kenmochi N.

Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes.

Nucleic Acids Res. 30(24): 5369-5375. 2002

Higa S, Maeda N, Kenmochi N, Tanaka T.

Location of 2(')-O-methyl nucleotides in 26S rRNA and methylation guide snoRNAs in Caenorhabditis elegans.

Biochem Biophys Res Commun. 297(5): 1344-1349. 2002

Yoshihama M, Uechi T, Asakawa S, Kawasaki K, Kato S, Higa S, Maeda N, Minoshima S, Tanaka T, Shimizu N, Kenmochi N.

The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.

Genome Res. 12(3): 379-390. 2002

Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T.

The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.

Genomics. 77(1-2): 65-70. 2001

Uechi T, Tanaka T, Kenmochi N.

A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders.

Genomics. 72(3): 223-230. 2001

Ion A, Crosby AH, Kremer H, Kenmochi N, Van Reen M, Fenske C, Van Der Burgt I, Brunner HG, Montgomery K, Kucherlapati RS, Patton MA, Page C, Mariman E, Jeffery S.

Detailed mapping, mutation analysis, and intragenic polymorphism identification in candidate Noonan syndrome genes MYL2, DCN, EPS8, and RPL6.

J Med Genet. 37(11): 884-886. 2000

Kenmochi N, Yoshihama M, Higa S, Tanaka T.

The human ribosomal protein L6 gene in a critical region for Noonan syndrome.

J Hum Genet. 45(5): 290-293. 2000

Kenmochi N

Molecular dissection of Ribosome: Genetic analysis of supramolecular systems

Bioscience and Industry 58: 27-30. 2000 (In Japanese)

Higa S, Yoshihama M, Tanaka T, Kenmochi N.

Gene organization and sequence of the region containing the ribosomal protein genes RPL13A and RPS11 in the human genome and conserved features in the mouse genome.

Gene. 240(2): 371-377. 1999

Kenmochi N.

Ribosomal abnormalities and human diseases.

Seikagaku. 71(3): 205-210. Review. 1999

Kenmochi N, Ashworth LK, Lennon G, Higa S, Tanaka T.

High-resolution mapping of ribosomal protein genes to human chromosome 19.

DNA Res. 5(4): 229-233. 1998

Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC.

A map of 75 human ribosomal protein genes.

Genome Res. 8(5): 509-523. 1998

Kenmochi N, Higa S, Yoshihama M, Tanaka T.

U14 snoRNAs are encoded in introns of human ribosomal protein S13 gene.

Biochem Biophys Res Commun. 228(2): 371-374. 1996